2μ,3μ,5μ-Tri-O-acetyl-6-azauridine, 6-Azauridine 2μ,3μ,5μ-triacetate, 6-AzUrd-TA, Azaribine, 2-β-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione 2μ,3μ,5μ-triacetate - Names and Identifiers
Name | 6-Azauridine 2',3',5'-triacetate
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Synonyms | cb304 Azaribine 2,3,5-Tri-O-acetyl-6-azauridine 2',3',5'-triacetyl-6-azauridine 6-Azauridine 2',3',5'-triacetate 6-Azauridine 2μ,3μ,5μ-triacetate, 6-AzUrd-TA, Azaribine 2-(2,3,5-tri-O-acetylpentofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione 4h)-dione,2-(2',3',5'-triacetyl-beta-d-ribofuranosyl)-as-triazine-5-(2h 2-beta-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione 2,3,5-triacetate 2-(2',3',5'-triacetyl-beta-d-ribofuranosyl)-as-triazine-3,5-(2h,4h)-dione 2-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione 2-(2-O,3-O,5-O-Triacetyl-β-D-ribofuranosyl)-1,2,4-triazine-3,5(2H,4H)-dione 2μ,3μ,5μ-Tri-O-acetyl-6-azauridine, 6-Azauridine 2μ,3μ,5μ-triacetate, 6-AzUrd-TA, Azaribine, 2-β-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione 2μ,3μ,5μ-triacetate
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CAS | 2169-64-4
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EINECS | 218-515-6 |
InChI | InChI=1/C14H17N3O9/c1-6(18)23-5-9-11(24-7(2)19)12(25-8(3)20)13(26-9)17-14(22)16-10(21)4-15-17/h4,9,11-13H,5H2,1-3H3,(H,16,21,22) |
2μ,3μ,5μ-Tri-O-acetyl-6-azauridine, 6-Azauridine 2μ,3μ,5μ-triacetate, 6-AzUrd-TA, Azaribine, 2-β-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione 2μ,3μ,5μ-triacetate - Physico-chemical Properties
Molecular Formula | C14H17N3O9
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Molar Mass | 371.3 |
Density | 1.3535 (rough estimate) |
Melting Point | 99-101°C(lit.) |
Boling Point | 501.01°C (rough estimate) |
Solubility | Chloroform (Slightly), Methanol (Slightly) |
Appearance | Solid |
Color | White to Light Yellow |
Storage Condition | Hygroscopic, -20°C Freezer, Under inert atmosphere |
Stability | Hygroscopic |
Refractive Index | 1.5700 (estimate) |
2μ,3μ,5μ-Tri-O-acetyl-6-azauridine, 6-Azauridine 2μ,3μ,5μ-triacetate, 6-AzUrd-TA, Azaribine, 2-β-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione 2μ,3μ,5μ-triacetate - Risk and Safety
Safety Description | S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
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WGK Germany | 2 |
RTECS | XY8577000 |
2μ,3μ,5μ-Tri-O-acetyl-6-azauridine, 6-Azauridine 2μ,3μ,5μ-triacetate, 6-AzUrd-TA, Azaribine, 2-β-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione 2μ,3μ,5μ-triacetate - Introduction
6-Azauridine 2 ',3',5 '-triacetate, also known as 6-Azauridine 2',3 ',5'-triacetate, is an organic compound with the chemical formula C12H15N3O7.
Nature:
6-Azauridine 2 ',3',5 '-triacetate is a white to pale yellow crystalline solid with a slight ammonia odor. It is less soluble in water and soluble in organic solvents such as ethanol and dimethyl sulfoxide.
Use:
6-Azauridine 2 ',3',5 '-triacetate is an anti-cancer drug and plays an important role in cancer chemotherapy. It can inhibit the proliferation of cancer cells by interfering with the synthesis of RNA and DNA.
Method:
6-Azauridine 2 ',3',5 '-triacetate can be prepared in many ways, including by chemical modification of uracil (Uridine).
Safety Information:
Under normal conditions of use, 6-Azauridine 2 ',3',5 '-triacetate is relatively safe. However, it may have an irritating effect on the skin, eyes and mucous membranes. Appropriate personal protective measures, such as gloves and goggles, are required when handling. In addition, the storage of 6-Azauridine 2 ',3',5 '-triacetate should be protected from direct sunlight and kept dry.
Last Update:2024-04-09 20:52:54